4
https://blast.ncbi.nlm.nih.gov/Blast.cgi
Collect, Compare and Understand Data In order to now know which virus we have in
front of us (in practice, usually even much more precisely, namely which virus strain), we
have to let the computer identify this sequence.
Collect Data This is particularly easy if you have created a database of virus sequences.
You already know their sequence because you have sequenced them before. As an exam
ple, let us consider HIV, the human immunodeficiency virus. With the help of the database,
it is easy to find out whether the sequence found by PCR for a virus in the blood matches
one of the entries in the database. Databases are fundamental in bioinformatics. They store
all the information and can then be used for further investigations.
1 Sequence Analysis: Deciphering the Language of Life